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Chen Yuguo/ Xu Feng's team makes new progress in cardiac arrest research

inputtime:2022-08-23 11:30:33 From:Qilu Hospital

Recently, the team led by Prof. Chen Yuguo and Prof. Xu Feng from Qilu Hospital of Shandong University, Shandong Provincial Clinical Medicine Research Center for Emergency and Critical Care Medicine published a paper titled “A national effort to improve outcomes for in-hospital cardiac arrest in China: The BASeline Investigation of Cardiac Arrest (BASIC-IHCA)” on Resuscitation Plus, a sister journal of Resuscitation, which is prestigious in the field of cardiac arrest resuscitation. The publication systematically introduced the design, implementation and operation of the in-hospital cardiac arrest investigation component(BASIC-IHCA)of the first nationwide, prospective, multicenter cardiac arrest cohort study in China led by the team of the Department of Emergency Medicine of Qilu Hospital - " Investigation on incidence, mortality and risk factors of cardiac arrest in Chinese population”. Prof. Xu Feng, Prof. Chen Yuguo, Prof. Zhang Guoqiang of China-Japan Friendship Hospital, and Prof. Lv Chuanzhu of Sichuan Provincial People’s Hospital are co-corresponding authors of this article. Wang Chunyi, Zheng Wen, and Zheng Jiaqi of the Department of Emergency Medicine are co-first authors.
Cardiac arrest is a serious threat to human health, and its high mortality and disability rate makes it a major public health issue attracting wide attention from the medical and social circles. Without a national cardiac arrest investigation in our country before, the lack of relevant epidemiological data is one of the problems which blocked the improvement of medical quality in this field.

The BASIC project, led by the team of the Department of Emergency Medicine, Qilu Hospital, was launched in more than 70 hospitals and pre-hospital emergency institutions across the country in 2019. Since then, in-hospital and out-of-hospital cardiac arrest cases have been continuously enrolling in. Up to now, BASIC-IHCA has successively enrolled over 50,000 IHCA cases in 40 participating hospitals across the country, and became the largest international first-class IHCA special disease database and follow-up cohort nationwide.

Professor Jerry P. Nolan, an authoritative expert in the field of cardiac arrest and also Chairman of the European Resuscitation Council, concurrently published a commentary titled "China joins the family of in-hospital cardiac arrest registries". He fully affirmed the BASIC-IHCA on its national representation, method standardization, and data integrity, etc., calling it an important milestone in the field of cardiac arrest in China. He said that BASIC-IHCA would present important Chinese data and experience to international counterparts, and he expected it would provide data support for the formulation and updating of international guidelines for cardiac arrest and cardiopulmonary resuscitation together with relevant investigations in Europe and the United States. 
The BASIC project will systematically show the epidemiology, treatment status and outcome of cardiac arrest in China for the first time, and provide data support and scientific basis for national and regional strategic deployment of cardiac arrest prevention, continuous improvement of medical quality and scientific and technological innovation. At the same time, the implementation methods and standards of the project will better promote the standardization and internationalization of the investigation of cardiac arrest in China. The BASIC project will further expand monitoring network across the country, promote continuous quality monitoring and improvement, improve patient’s prognosis, and contribute to the early realization of the important strategic goal of "Healthy China 2030".
Prof. Chen Yuguo / Prof. Xu Feng’s team has made a series of research progress in the field of cardiac arrest and resuscitation. Relevant research results have been published in JAMA Cardiology, Frontiers in Pharmacology, European Heart Journal, JAMA, JCI Insight and other international journals. This project is supported by the National Science and Technology Basic Resources Survey Project (2018FY100600).
 
By Sun Yingtao, Ji Haoyi